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Simultaneous bright and dark field OCT with a polarization sensitive detection (Conference Presentation)
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Paper Abstract

A polarization sensitive extension was implemented into our bright and dark field optical coherence tomography (BRAD-OCT) system. The few-mode fiber detection enables the analysis of the scattering profiles of biological tissues by sensing the sample backscattering information at larger angles through the different fiber modes, enabling simultaneous detection of the bright and dark field. Since the polarization state of light scattered at different angles strongly depends on the tissue microstructure, the polarization sensitive detection improves the imaging capabilities of BRAD-OCT. The system performance was evaluated in phantoms of differently sized microparticles, showing different polarization characteristics for the different fiber modes. Preliminary analysis has been performed in ex vivo brain tissue, where stokes vectors analysis of the different modal images reconstructed by our BRAD-OCT setup indicates that polarization sensitive in combination with BRAD detection is a promising tool for investigating the scattering properties of biological tissues.

Paper Details

Date Published: 4 March 2019
Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108671T (4 March 2019); doi: 10.1117/12.2511454
Show Author Affiliations
Pablo Eugui , Medizinische Univ. Wien (Austria)
Conrad Merkle, Medizinische Univ. Wien (Austria)
Danielle J. Harper, Medizinische Univ. Wien (Austria)
Antonia Lichtenegger, Medizinische Univ. Wien (Austria)
Marco Augustin, Medizinische Univ. Wien (Austria)
Martina Muck, Institute of Neurology, Medizinische Univ. Wien (Austria)
Adelheid Wöhrer, Institut für Neurologie, Medizinische Univ. Wien (Austria)
Christoph K. Hitzenberger, Medizinische Univ. Wien (Austria)
Bernhard Baumann, Medizinische Univ. Wien (Austria)

Published in SPIE Proceedings Vol. 10867:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII
James G. Fujimoto; Joseph A. Izatt, Editor(s)

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