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Sub-millimeter diameter high-resolution rotary-pullback fibre optic endoscope for RGB in-vivo imaging (Conference Presentation)
Author(s): Andrea Louise Buenconsejo; Geoffrey Hohert; Ian Janzen; Anthony Lee; Pierre Lane; Calum MacAulay

Paper Abstract

The early detection of cancer brings increased success in the treatment of cancer patients. A prototype sub-millimeter diameter high resolution fibre endoscope for the in-vivo imaging in oral, lung, cervix, ovarian and pancreas sites for the early detection and delineation of cancers is currently in its early stages of development. The endoscope is to utilize a combination of rotary and pullback motion to allow a wide field-of-view while capturing high-resolution (10 to 20 um) RGB images. In this system an RGB laser module uses the core of a dual-clad fibre for illumination and the inner cladding for detection to achieve real time in-vivo reflectance imaging . Signal detection for each laser (RGB) has been tested using a white card printed with black lines of varying widths. The contrast between the white and black portions of the card and the Signal to Noise Ratio (SNR) for the pullback mechanism of the system were determined. The card contrast values for red, green and blue light were calculated to be 25.0, 15.6 and 8.3 respectively, while the SNR values were 180, 155, and 154 respectively. These values suggest that the performance of the system is wavelength dependent. The imaging performance characteristics of the endoscope with rotary and pullback motion combined will be further quantified, and results and images will be presented.

Paper Details

Date Published: 4 March 2019
Proc. SPIE 10854, Endoscopic Microscopy XIV, 108540P (4 March 2019); doi: 10.1117/12.2510772
Show Author Affiliations
Andrea Louise Buenconsejo, BC Cancer Research Ctr. (Canada)
Geoffrey Hohert, BC Cancer Research Ctr. (Canada)
Ian Janzen, BC Cancer Research Ctr. (Canada)
Anthony Lee, BC Cancer Research Ctr. (Canada)
Pierre Lane, BC Cancer Research Ctr. (Canada)
Calum MacAulay, BC Cancer Research Ctr. (Canada)

Published in SPIE Proceedings Vol. 10854:
Endoscopic Microscopy XIV
Guillermo J. Tearney M.D.; Thomas D. Wang; Melissa J. Suter, Editor(s)

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