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Compensation of refractive index variation in optical coherence tomography images
Author(s): Zahra Turani; Emad Fatemizadeh; Steven Daveluy; Darius Mehregan; Rayyan Manwar; Mohammad Avanaki
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Paper Abstract

Optical coherence tomography (OCT) imaging is a high resolution and non-invasive imaging modality that provides cross-sectional images of a tissue. The time of flight in the signal processing of the OCT system is calculated based on a constant refractive index. Different layers of the complex tissues however have different refractive indices. This issue prompts pixels in the image to be misplaced and that makes it difficult for the physicians to have an accurate diagnosis of abnormalities based on OCT imaging, e.g., in measurement of the thickness of skin layers. In this paper, we propose a novel post-processing method to correct for the refractive index. The proposed method is based on imaging a tissue to which a needle has been penetrated.

Paper Details

Date Published: 5 March 2019
PDF: 7 pages
Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108672W (5 March 2019); doi: 10.1117/12.2510561
Show Author Affiliations
Zahra Turani, Sharif Univ. of Technology (United States)
Wayne State Univ. (United States)
Emad Fatemizadeh, Sharif Univ. of Technology (Iran, Islamic Republic of)
Steven Daveluy, Wayne State Univ. (United States)
Darius Mehregan, Wayne State Univ. (United States)
Rayyan Manwar, Wayne State Univ. (United States)
Mohammad Avanaki, Wayne State Univ. (United States)


Published in SPIE Proceedings Vol. 10867:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII
James G. Fujimoto; Joseph A. Izatt, Editor(s)

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