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Esophageal OCT using endoscope-coupled paddle probe (Conference Presentation)
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Paper Abstract

Video endoscopy remains the most common means of examining the upper gastrointestinal tract. However, white-light widefield imagery is limited in diagnostic sensitivity and specificity for conditions such as Barrett’s esophagus. To provide cross-sectional imaging that yields more accurate diagnosis, optical coherence tomography (OCT) has been implemented for upper GI screening and diagnosis in several form factors, such as inflatable balloons and tethered capsules. We now present an alternative configuration for esophageal OCT. Our OCT probe is contained within an articulating paddle that attaches to the end of an upper GI endoscope via flexible cuff. This arrangement allows regions of interest to be visually identified by the physician operating the endoscope and targeted for OCT imaging by application of the paddle. The probe housing was 3D printed using biocompatible dental resin. The flexible cuff was also 3D printed using a silicone-based resin to allow a tight fit to the endoscope. The optical probe was a rotating fiber-optic design, consisting of a gradient-index lens and prism on the distal end, wound steel torque coil, a polymer sheath, and a fiber-optic rotary junction. The OCT system was a spectral domain configuration with custom spectrometer operating at 20,000 A-lines per second. The illumination source was a superluminescent diode centered at 1310 nm. A clinical pilot study at the University of North Carolina Endoscopy Center is scheduled to begin imminently.

Paper Details

Date Published: 4 March 2019
Proc. SPIE 10854, Endoscopic Microscopy XIV, 108540K (4 March 2019); doi: 10.1117/12.2510237
Show Author Affiliations
Yang Zhao, Duke Univ. (United States)
Kengyeh K. Chu, Duke Univ. (United States)
Michael Crose, Duke Univ. (United States)
Yaa Ofori-Marfoh, The Univ. of North Carolina School of Medicine (United States)
Holly Cirri, The Univ. of North Carolina School of Medicine (United States)
Nicholas J. Shaheen, The Univ. of North Carolina School of Medicine (United States)
Adam P. Wax, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 10854:
Endoscopic Microscopy XIV
Guillermo J. Tearney M.D.; Thomas D. Wang; Melissa J. Suter, Editor(s)

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