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Stimulated Raman scattering-spectroscopic optical coherence tomography (SRS-SOCT): theory, applications and new developments
Author(s): Francisco E. Robles
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Paper Abstract

Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) is a recently developed molecular imaging technique that leverages the spatial and spectral multiplexing capabilities of SOCT with the molecular sensitivity and specificity of SRS for fast, tomographic, label-free molecular imaging. Here we present a theoretical framework for SRS-SOCT, discuss its advantages and limitations, and show experimental results from excised human adipose tissue. We also discuss our recent efforts in developing a novel light source, based on a coherently broadened laser, that is specifically tailored for SRS-SOCT. Implications of this label-free, molecular imaging technique for biomedical applications are discussed.

Paper Details

Date Published: 4 March 2019
PDF: 7 pages
Proc. SPIE 10890, Label-free Biomedical Imaging and Sensing (LBIS) 2019, 108900N (4 March 2019); doi: 10.1117/12.2510212
Show Author Affiliations
Francisco E. Robles, Georgia Institute of Technology and Emory Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 10890:
Label-free Biomedical Imaging and Sensing (LBIS) 2019
Natan T. Shaked; Oliver Hayden, Editor(s)

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