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Vibrating dichroic MEMS scanner based line scan multiphoton endomicroscope
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Paper Abstract

To achieve optical biopsy for gastro-intestinal (GI) endosopy with the use of nonlinear optical (NLO) endomicroscopes, integration of NLO technology with the design of a conventional flexible GI endoscope is necessary. One key challenge has been to design an NLO distal tip which can be compatible with flexible GI endoscopy retroflexion curvature radius as small as 20 mm to provide bending angle up to 210 degrees; the state-of-the-art NLO miniaturized design still consists of a long rigid “needle” shape probe at the distal end that can be damaged during the retroflex procedure when passing through the instrument channel of a flexible GI endoscope for in vivo imaging. To circumvent this design challenge, authors present a line scan multiphoton endomicroscope utilizing a novel simplified microelectromechanical systems (MEMS) scanner. This unique MEMS scanner consists of a customized single-axis dichroic MEMS scanner (SADMS) and vibrates at the back focal point of a customized micro-objective lens. This work demonstrates the new NLO scanner design can be compatible with conventional flexible GI endoscope to offer in situ functional microscopic imaging capability.

Paper Details

Date Published: 4 March 2019
PDF: 12 pages
Proc. SPIE 10931, MOEMS and Miniaturized Systems XVIII, 1093116 (4 March 2019); doi: 10.1117/12.2510040
Show Author Affiliations
Yingshun Xu, Massachusetts Institute of Technology (United States)
Tianjin Medical Univ. (China)
Jin Cheng, Xi'an Technological Univ. (China)
China Key System Integrated Circuit Co., Ltd. (China)
Naitao Xu, China Key System Integrated Circuit Co., Ltd. (China)
Lanping Zhu, Tianjin Medical Univ. General Hospital (China)
Yuzhu Cao, Tianjin Medical Univ. (China)
Bei Fang, Tianjin Medical Univ. (China)
Xin Chen, Tianjin Medical Univ. General Hospital (China)
Suogang Wang, Tianjin Medical Univ. (China)
Peter T. C. So, Massachusetts Institute of Technology (United States)


Published in SPIE Proceedings Vol. 10931:
MOEMS and Miniaturized Systems XVIII
Wibool Piyawattanametha; Yong-Hwa Park; Hans Zappe, Editor(s)

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