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Multimodal multiphoton tomograph using a compact femtosecond fiber laser
Author(s): Karsten König; Ana Batista; Aisada König; Hans Georg Breunig
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Paper Abstract

Multiphoton tomography based on near infrared femtosecond laser technology has become a versatile high-resolution clinical- and research-imaging tool. Here, we report on a novel moveable multimodal tomograph, the MPTcompact, based on an ultracompact chiller-free fiber-laser system. The tomograph provides in vivo optical biopsies with subcellular resolution as well as optical metabolic imaging capability based on two-photon autofluorescence, second harmonic generation, fluorescence lifetime imaging, reflectance confocal microscopy, and white light CCD imaging. Applications include cancer detection, skin research, cornea research, and in situ evaluation of anti-ageing drugs and pharmaceuticals.

Paper Details

Date Published: 22 February 2019
PDF: 6 pages
Proc. SPIE 10882, Multiphoton Microscopy in the Biomedical Sciences XIX, 108821A (22 February 2019); doi: 10.1117/12.2509551
Show Author Affiliations
Karsten König, JenLab GmbH (Germany)
Univ. des Saarlandes (Germany)
Ana Batista, Univ. des Saarlandes (Germany)
Aisada König, JenLab GmbH (Germany)
Univ. des Saarlandes (Germany)
Hans Georg Breunig, JenLab GmbH (Germany)
Univ. des Saarlandes (Germany)

Published in SPIE Proceedings Vol. 10882:
Multiphoton Microscopy in the Biomedical Sciences XIX
Ammasi Periasamy; Peter T. C. So; Karsten König, Editor(s)

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