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Thermo-elastic optical coherence tomography
Author(s): Tianshi Wang; Tom Pfeiffer; Wolfgang Wieser; Heleen van Beusekom; Wolfgang Draxinger; Antonius F. W. van der Steen; Robert Huber; Gijs van Soest
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Paper Abstract

The absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue. A sub-micrometer scale displacement occurs within a few microseconds after the pulse arrival. We investigate the thermo-elastic deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. An analysis of the results shows that the displacement is dominated by the optical absorption. By tuning the excitation wavelength, thermo-elastic displacement spectrum can be extracted, showing the similar features as optical absorption spectrum. By choosing proper excitation wavelength, targeted tissue type can be highlighted, which further enables a new imaging modality, so called thermo-elastic OCT.

Paper Details

Date Published: 22 February 2019
PDF: 4 pages
Proc. SPIE 10867, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII, 108672C (22 February 2019); doi: 10.1117/12.2508852
Show Author Affiliations
Tianshi Wang, Erasmus Univ. Medical Ctr. (Netherlands)
Tom Pfeiffer, Univ. zu Lübeck (Germany)
Wolfgang Wieser, Optores GmbH (Germany)
Heleen van Beusekom, Erasmus Univ. Medical Ctr. (Netherlands)
Wolfgang Draxinger, Univ. zu Lübeck (Germany)
Antonius F. W. van der Steen, Erasmus Univ. Medical Ctr. (Netherlands)
Shenzen Institute of Advanced Technology (China)
Delft Univ. (Netherlands)
Robert Huber, Univ. zu Lübeck (Germany)
Gijs van Soest, Erasmus Univ. Medical Ctr. (Netherlands)


Published in SPIE Proceedings Vol. 10867:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIII
James G. Fujimoto; Joseph A. Izatt, Editor(s)

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