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Long-term photoacoustic brain imaging in a freely moving rat
Author(s): Qian Chen; Lei Xi
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Paper Abstract

Photoacoustic microscopy (PAM) is an emerging technique extensively used to study brain activities. However, limited by the size and performance of optical/acoustic scanners, existing ORPAMs are still bulky, heavy, and suffer from low imaging quality/speed. Here, we develop a wearable ORPAM probe featuring small, light, fast, and cellular imaging capability. To evaluate the probe, we monitored the cerebral vascular network within two hours and demonstrated that the microscope was stable enough to study long-term brain hemodynamics in a freely moving rat.

Paper Details

Date Published: 1 March 2019
PDF: 5 pages
Proc. SPIE 10865, Neural Imaging and Sensing 2019, 108650W (1 March 2019); doi: 10.1117/12.2507790
Show Author Affiliations
Qian Chen, Southern Univ. of Science and Technology of China (China)
Lei Xi, Southern Univ. of Science and Technology of China (China)

Published in SPIE Proceedings Vol. 10865:
Neural Imaging and Sensing 2019
Qingming Luo; Jun Ding; Ling Fu, Editor(s)

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