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Resolution optimized prism-based SPR imaging for the study of individual bacteria interactions with surfaces
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Paper Abstract

Bacterial pathogen contamination is the leading cause of both foodborne and hospital-acquired diseases. Therefore, there is a constant need for more effective, reliable and easy-to-use microbiology study techniques and detection systems. This is critical, as pathogenic contamination has become a central issue in the food industry and healthcare. This paper describes the novel use of resolution-optimized prism-based surface plasmon resonance imaging (resolution around the size of a bacteria) and data processing to further understand the behavior of individual bacteria near specifically engineered surfaces. We show that our technique is effective for both the dynamic study of individual bacteria behavior near interface on a statistically representative sample, and their interactions with chemically functionalized surfaces.

Paper Details

Date Published: 7 March 2019
PDF: 13 pages
Proc. SPIE 10894, Plasmonics in Biology and Medicine XVI, 108940J (7 March 2019); doi: 10.1117/12.2507770
Show Author Affiliations
Marine Boulade, Univ. Grenoble Alpes (France)
Univ. de Sherbrooke (Canada)
Thierry Livache, Univ. Grenoble Alpes (France)
Paul G. Charette, Univ. de Sherbrooke (Canada)
Michael Canva, Univ. de Sherbrooke (Canada)
Loïc Leroy, Univ. Grenoble Alpes (France)

Published in SPIE Proceedings Vol. 10894:
Plasmonics in Biology and Medicine XVI
Tuan Vo-Dinh; Ho-Pui A. Ho; Krishanu Ray, Editor(s)

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