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Terahertz spectra of drug-laden magnetic nanoparticles
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Paper Abstract

Drag-laden magnetic nanoparticles can deliver drugs to a zone of ischemic damage for various purposes of clinical medicine. THz spectroscopy of nanoparticles with adsorbed organic and biological molecules could enable estimation of drug delivery efficiency of the nanoparticles sample and curative effect of delivering chemical substance. The first task of this work was to simulate the contribution of nanoparticles and the shell of organic molecules (glycose) to the dielectric properties of the pressed pellets, consisting of the polyethylene and nanoparticles. The second task of this paper was to study experimentally the possibility of using terahertz radiation for spectral diagnosis of NPs based on iron oxide in a biologically inert shell of silicon dioxide drug-laden with a glycose.

Paper Details

Date Published: 7 March 2019
PDF: 9 pages
Proc. SPIE 10892, Colloidal Nanoparticles for Biomedical Applications XIV, 108920L (7 March 2019); doi: 10.1117/12.2506870
Show Author Affiliations
Olga A. Smolyanskaya, ITMO Univ. (Russian Federation)
Valery N. Trukhin, ITMO Univ. (Russian Federation)
Ioffe PhysicoTechnical Institute (Russian Federation)
Polina G. Gavrilova, ITMO Univ. (Russian Federation)
Evgeniy L. Odlyanitskiy, ITMO Univ. (Russian Federation)
Anna V. Semenova, Institute for Physics of Microstructures (Russian Federation)
Institute of Applied Physics (Russian Federation)
Quentin Cassar, IMS Lab., CNRS, Univ. de Bordeaux (France)
Jean-Paul Guillet, IMS Lab., CNRS, Univ. de Bordeaux (France)
Patrick Mounaix, IMS Lab., CNRS, Univ. de Bordeaux (France)
Kamil G. Gareev, Saint Petersburg Electrotechnical Univ. "LETI" (Russian Federation)
Dmitry V. Korolev, Almazov National Medical Research Ctr. (Russian Federation)

Published in SPIE Proceedings Vol. 10892:
Colloidal Nanoparticles for Biomedical Applications XIV
Marek Osiński; Wolfgang J. Parak, Editor(s)

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