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Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging
Author(s): Tianshi Wang; Tom Pfeiffer; Joost Daemen; Frits Mastik; Wolfgang Wieser; A. F. W. van der Steen; Robert Huber; Gijs van Soest
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Paper Abstract

We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

Paper Details

Date Published: 26 February 2019
PDF: 5 pages
Proc. SPIE 10855, Diagnostic and Therapeutic Applications of Light in Cardiology 2019, 1085503 (26 February 2019); doi: 10.1117/12.2506151
Show Author Affiliations
Tianshi Wang, Erasmus Univ. Medical Ctr. (Netherlands)
Tom Pfeiffer, Institut für Biomedizinische Optik, Univ. zu Lübeck (Germany)
Joost Daemen, Erasmus Univ. Medical Ctr. (Netherlands)
Frits Mastik, Erasmus Univ. Medical Ctr. (Netherlands)
Wolfgang Wieser, Optores GmbH (Germany)
A. F. W. van der Steen, Erasmus Univ. Medical Ctr. (Netherlands)
Shenzhen Institutes of Advanced Technology (China)
Delft Univ. of Technology (Netherlands)
Robert Huber, Institut für Biomedizinische Optik, Univ. zu Lübeck (Germany)
Gijs van Soest, Erasmus Univ. Medical Ctr. (Netherlands)


Published in SPIE Proceedings Vol. 10855:
Diagnostic and Therapeutic Applications of Light in Cardiology 2019
Kenton W. Gregory M.D.; Laura Marcu, Editor(s)

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