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International Photoacoustic Standardisation Consortium (IPASC): overview (Conference Presentation)
Author(s): Sarah Bohndiek; Joanna Brunker; Janek Gröhl; Lina Hacker; James Joseph; William C. Vogt; Paolo Armanetti; Hisham Assi; Jeffrey C. Bamber; Paul C. Beard; Thomas Berer; Richard Bouchard; Kimberly A. Briggman; Lucia Cavigli; Bryan Clingman; Ben T. Cox; Adrien E. Desjardins; Andrew Heinmiller; Jeesong Hwang; Eno Hysi; Aoife Ivory; Jithin Jose; Thomas Kirchner; Jan Klohs; Lena Maier-Hein; Efthymios Maneas; Julia Mannheim; Srirang Manohar; Lacey McNally; Luca Menichetti; Steven Miller; Stefan Morscher; Ruiqing Ni; Yoko Okamura; Malini C. Olivo; Marty Pagel; Geoff Parker; Anna Pelagotti; Antonio Pifferi; Srinath Rajagopal; Fulvio Ratto; Daniel Razansky; Lisa M. Richards; Avihai Ron; Mithun Kuniyil Ajith Singh; Maximillian Waldner; Kun Wang; Lihong V. Wang; Wenfeng Xia; Bajram Zeqiri
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Paper Abstract

The International Photoacoustic Standardisation Consortium (IPASC) emerged from SPIE 2018, established to drive consensus on photoacoustic system testing. As photoacoustic imaging (PAI) matures from research laboratories into clinical trials, it is essential to establish best-practice guidelines for photoacoustic image acquisition, analysis and reporting, and a standardised approach for technical system validation. The primary goal of the IPASC is to create widely accepted phantoms for testing preclinical and clinical PAI systems. To achieve this, the IPASC has formed five working groups (WGs). The first and second WGs have defined optical and acoustic properties, suitable materials, and configurations of photoacoustic image quality phantoms. These phantoms consist of a bulk material embedded with targets to enable quantitative assessment of image quality characteristics including resolution and sensitivity across depth. The third WG has recorded details such as illumination and detection configurations of PAI instruments available within the consortium, leading to proposals for system-specific phantom geometries. This PAI system inventory was also used by WG4 in identifying approaches to data collection and sharing. Finally, WG5 investigated means for phantom fabrication, material characterisation and PAI of phantoms. Following a pilot multi-centre phantom imaging study within the consortium, the IPASC settled on an internationally agreed set of standardised recommendations and imaging procedures. This leads to advances in: (1) quantitative comparison of PAI data acquired with different data acquisition and analysis methods; (2) provision of a publicly available reference data set for testing new algorithms; and (3) technical validation of new and existing PAI devices across multiple centres.

Paper Details

Date Published: 4 March 2019
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Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108781N (4 March 2019); doi: 10.1117/12.2506044
Show Author Affiliations
Sarah Bohndiek, Univ. of Cambridge (United Kingdom)
Joanna Brunker, Univ. of Cambridge (United Kingdom)
Janek Gröhl, Deutsches Krebsforschungszentrum (Germany)
Lina Hacker, Univ. of Cambridge (United Kingdom)
James Joseph, Univ. of Cambridge (United Kingdom)
William C. Vogt, U.S. Food and Drug Administration (United States)
Paolo Armanetti, Univ. di Pisa (Italy)
Hisham Assi, Ryerson Univ. (Canada)
Jeffrey C. Bamber, The Institute of Cancer Research (United Kingdom)
Paul C. Beard, Univ. College London (United Kingdom)
Thomas Berer, Research Ctr. for Non Destructive Testing GmbH (Austria)
Richard Bouchard, The Univ. of Texas M. D. Anderson Cancer Ctr. (United States)
Kimberly A. Briggman, National Institute of Standards and Technology (United States)
Lucia Cavigli, Istituto di Fisica Applicata "Nello Carrara" (Italy)
Bryan Clingman, Seno Medical Instruments, Inc. (United States)
Ben T. Cox, Univ. College London (United Kingdom)
Adrien E. Desjardins, Univ. College London (United Kingdom)
Andrew Heinmiller, FUJIFILM VisualSonics, Inc. (Canada)
Jeesong Hwang, National Institute of Standards and Technology (United States)
Eno Hysi, Ryerson Univ. (Canada)
Aoife Ivory, National Physical Lab. (United Kingdom)
Jithin Jose, FUJIFILM VisualSonics, Inc. (Netherlands)
Thomas Kirchner, Deutsches Krebsforschungszentrum (Germany)
Jan Klohs, ETH Zurich (Switzerland)
Lena Maier-Hein, Deutsches Krebsforschungszentrum (Germany)
Efthymios Maneas, Univ. College London (United Kingdom)
Julia Mannheim, Universitätsklinikum Tübingen (Germany)
Srirang Manohar, Univ. of Twente (Netherlands)
Lacey McNally, Virginia Polytechnic Institute and State Univ. (United States)
Wake Forest Univ. (United States)
Luca Menichetti, Istituto di Fisiologia Clinica (Italy)
Steven Miller, Seno Medical Instruments, Inc. (United States)
Stefan Morscher, iThera Medical GmbH (Germany)
Ruiqing Ni, ETH Zurich (Switzerland)
Yoko Okamura, Canon Medical Systems Corp. (Japan)
Malini C. Olivo, Singapore Bioimaging Consortium (Singapore)
Marty Pagel, Banner MD Anderson Cancer Ctr. (United States)
Geoff Parker, The Univ. of Manchester (United Kingdom)
Anna Pelagotti, European Comsission (Belgium)
Antonio Pifferi, Politecnico di Milano (Italy)
Srinath Rajagopal, National Physical Lab. (United Kingdom)
Fulvio Ratto, Istituto di Fisica Applicata "Nello Carrara" (Italy)
Daniel Razansky, Helmholtz Zentrum München GmbH (Germany)
Lisa M. Richards, Seno Medical Instruments, Inc. (United States)
Avihai Ron, Helmholtz Zentrum München GmbH (Germany)
Mithun Kuniyil Ajith Singh, Cyberdyne, Inc. (Japan)
Maximillian Waldner, Friedrich-Alexander-Univ. Erlangen-Nürnberg (Germany)
Kun Wang, Institute of Automation (China)
Lihong V. Wang, Caltech (United States)
Wenfeng Xia, Univ. College London (United Kingdom)
Bajram Zeqiri, National Physical Lab. (United Kingdom)


Published in SPIE Proceedings Vol. 10878:
Photons Plus Ultrasound: Imaging and Sensing 2019
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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