Share Email Print
cover

Proceedings Paper • new

Conformal initialization for shape analysis applications in SlicerSALT
Author(s): Zhengyang Fang; Mahmoud Mostapha; Juan Prieto; Martin Styner
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Shape analysis is an important method used in neuroimaging research community due to its potential to precisely locate morphological changes between healthy and pathological structures. A popular shape analysis framework in the neuroimaging community is based on the encoding surface locations as spherical harmonics for a representation called SPHARM-PDM. The SPHARM-PDM pipeline takes a set of brain segmentation of a single brain structure (for example, hippocampus) as input and converts them into a corresponding spherical harmonic description (SPHARM), which is then sampled into triangulated surface (SPHARM-PDM). At present, the SPHARM-PDM pipeline utilizes an area-preserving optimization of the spherical mapping based on an initial heat-equation based mapping of the surface mesh to the unit sphere. In the case of objects with complex shape, this initial spherical mapping suffers from a high degree of mapping distortion that cannot always be corrected by the following optimization procedure. Here we proposed the use of an alternative initialization based on a conformal flattening. This method adopts a bijective angle preserving conformal flattening scheme to replace the heat equation mapping scheme as initialization for use in the SPHARM-PDM pipeline. After quantitative measures of shape calculated from various complex structures, we concluded that in most cases, the new pipeline produced dramatically better results than the old pipeline. The main contribution of this paper is a command line tool based on the Slicer Execution Model, which merges the conformal flattening into the SPHARM-PDM pipeline for use in the SALT shape analysis toolbox.

Paper Details

Date Published: 15 March 2019
PDF: 8 pages
Proc. SPIE 10953, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging, 1095326 (15 March 2019); doi: 10.1117/12.2503894
Show Author Affiliations
Zhengyang Fang, The Univ. of North Carolina at Chapel Hill (United States)
Mahmoud Mostapha, The Univ. of North Carolina at Chapel Hill (United States)
Juan Prieto, The Univ. of North Carolina at Chapel Hill (United States)
Martin Styner, The Univ. of North Carolina at Chapel Hill (United States)


Published in SPIE Proceedings Vol. 10953:
Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging
Barjor Gimi; Andrzej Krol, Editor(s)

© SPIE. Terms of Use
Back to Top