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Label-free imaging using multimodal microscopy in vivo and in vitro
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Paper Abstract

Many imaging technologies, such as two photon microscopy (TPM), second generation microscopy (SHG) and photoacoustic microscopy (PAM), have successfully demonstrated the ability to extract anatomical, functional and molecular information of biological samples. However, they always fail to obtain comprehensive information from biological tissue due to single imaging modality. To address this limitation, we developed a multimodal microscopy with fully integrated PAM, TPM and SHG. The home-built multimodal microscopy system enable label-free imaging of biomedical tissue with sub-micron resolution in vivo and in vitro. The results may offer a new tool to provide the capable of fast comprehensive information capturing for biological studies.

Paper Details

Date Published: 23 October 2018
PDF: 6 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108203D (23 October 2018); doi: 10.1117/12.2502490
Show Author Affiliations
Jiuling Liao, Shenzhen Institutes of Advanced Technology (China)
Tingai Chen, Shenzhen Institutes of Advanced Technology (China)
Yufeng Gao, Shenzhen Institutes of Advanced Technology (China)
Ting Wu, Shenzhen Institutes of Advanced Technology (China)
Jia Yu, Shenzhen Institutes of Advanced Technology (China)
Xianyuan Xia, Shenzhen Institutes of Advanced Technology (China)
Wei Zheng, Shenzhen Institutes of Advanced Technology (China)


Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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