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Proceedings Paper

Polymeric micelles deliver phthalocyanine for enhancement in vitro photodynamic efficacy
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Paper Abstract

A novel polymeric nanoparticle was developed between the negatively charged dendrimer phthalocyanine and positively triblock copolymer for the use as an effective photosensitizer in photodynamic therapy. The intracellular uptake of dendrimer phthalocyanines in HeLa cell was significantly enhanced by encapsulated into nanoparticles. The photocytotoxicity of dendrimer phthalocyanines incorporated into polymeric micelles was also increased. The presence of nanoparticles located induced efficient cell death.

Paper Details

Date Published: 6 December 2018
PDF: 8 pages
Proc. SPIE 10816, Advanced Optical Imaging Technologies, 108161M (6 December 2018); doi: 10.1117/12.2501228
Show Author Affiliations
Kuizhi Chen, Fujian Normal Univ. (China)
Ruotao Guo, Fujian Normal Univ. (China)
Shuanghuang Xiao, Fujian Normal Univ. (China)
Qiaohao Ye, Fujian Normal Univ. (China)
Hongqin Yang, Fujian Normal Univ. (China)
Yiru Peng, Fujian Normal Univ. (China)


Published in SPIE Proceedings Vol. 10816:
Advanced Optical Imaging Technologies
Xiao-Cong Yuan; Kebin Shi; Michael G. Somekh, Editor(s)

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