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Numerical simulation and experimental study on photo-thermal damage distribution of skin
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Paper Abstract

Photo-thermal response is one of the basis processes of laser irradiated tissue, dominating the laser surgical process and depending on the effect of laser treatment. To better investigate the interaction between ablative laser and skin, and more understand the light distribution and temperature distribution during the laser irradiation. Numerical simulation, which based on finite elements method (FEM), was used to solve the bio-heat and the thermal damage equations. Laser parameters can be adjustable during the process of surgery. Optical transmission, scattering coefficient and absorption coefficient in bio-tissue under laser irradiation were carried out to analyze the thermal response, which resulted from the absorbed light energy. And then, optical coherence tomography (OCT) was applied to study the injure in mice skin. The result is consistent to Numerical simulation, which will help to improve the laser therapy.

Paper Details

Date Published: 23 October 2018
PDF: 12 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108202W (23 October 2018); doi: 10.1117/12.2501179
Show Author Affiliations
Jiatian Li, Fujian Normal Univ. (China)
Huaqing Wu, Fujian Normal Univ. (China)
Shulian Wu, Fujian Normal Univ. (China)

Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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