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Assessment of tissues' inhomogeneous optical properties by a cost-effective microscope based on LED illumination
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Paper Abstract

Assessing tissues’ inhomogeneous optical properties is helpful for diagnosis, but high-cost measurement and experimental setups limit its development, data collecting and applications. In this paper, a portable microscope is proposed to assess the inhomogeneous optical properties of the sample. With a LED illumination, accurate quantitative phase (QP) map can be recovered from 5 intensity images captured at different axial positions. Then based on the scattering-phase theorem and statistical dispersion relation (SDR), the inhomogeneous optical properties of the sample can be quantitatively assessed from these QP maps. In contrast to DHM and SLIM, our setup is cost-effective, use-flexible, and with a small amount of data acquisition, thus having the potential to promote the development of assessing tissues’ inhomogeneous optical properties, especially in resource-limited areas.

Paper Details

Date Published: 23 October 2018
PDF: 10 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108202O (23 October 2018); doi: 10.1117/12.2501126
Show Author Affiliations
Yinxu Bian, Zhejiang Univ. (China)
Qiulan Liu, Zhejiang Univ. (China)
Cuifang Kuang, Zhejiang Univ. (China)
Shanxi Univ. (China)
Haifeng Li, Zhejiang Univ. (China)


Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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