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Proceedings Paper

Multiphoton imaging of gastric intestinal metaplasia
Author(s): Lianhuang Li; Deyong Kang; Changyin Feng; Zhenlin Zhan; Shuangmu Zhuo; Yongjian Zhou; Jianxin Chen
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Paper Abstract

Intestinal metaplasia has been widely considered as a precursor of gastric cancer, and early detection and accurate diagnosis will have important clinical significance. Therefore, multiphoton microscopy using two-photon excited fluorescence combined with second harmonic generation was used for investigating gastric intestinal metaplasia in this work, and imaging results showed that this microscope has the ability to directly differentiate this lesion in the absence of labels. This study highlights the potential of multiphoton microscopy as a diagnostic tool for label-freely identifying gastric intestinal metaplasia.

Paper Details

Date Published: 23 October 2018
PDF: 7 pages
Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108201F (23 October 2018); doi: 10.1117/12.2500391
Show Author Affiliations
Lianhuang Li, Fujian Normal Univ. (China)
Deyong Kang, Fujian Medical Univ. Union Hospital (China)
Changyin Feng, Fujian Medical Univ. Union Hospital (China)
Zhenlin Zhan, Fujian Normal Univ. (China)
Shuangmu Zhuo, Fujian Normal Univ. (China)
Yongjian Zhou, Fujian Medical Univ. Union Hospital (China)
Jianxin Chen, Fujian Normal Univ. (China)

Published in SPIE Proceedings Vol. 10820:
Optics in Health Care and Biomedical Optics VIII
Qingming Luo; Xingde Li; Ying Gu; Yuguo Tang, Editor(s)

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