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Proceedings Paper

Nonpenetrating keratoprosthesis
Author(s): Bernard Duchesne; Jean-Marie A. Parel; Sabine Gautier; Fabrice Manns; Hiroyuki Kondo; Emmanuel Lacombe; Jean-Marc Legeais; E. Alfonso
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Paper Abstract

The concept and invention of the non-penetrating keratoprosthesis were described in 1991 by Legeais, Parel, Villain, Tseng and Lacombe. The main advantage of the non-penetrating keratoprosthesis is that Descemet's membrane and the endothelium are kept in place. Therefore, the risk of endophtalmitis may be reduced, and anterior chamber effraction and pressure modification may be avoided. The prosthesis was designed with a 7 mm diameter optic and a 10 mm diameter skirt made of expanded polytetrafluoroethylene (ePTFE). A flange in teflon was used to ensure biointegration of the prosthesis. We carried out 3 preliminary studies in Eye-Bank eyes and rabbits, in order to assess surgical feasibility, Descemet membrane strength, and biocompatibility of different types of polymers. We are also currently conducting a study on rabbits.

Paper Details

Date Published: 17 May 1996
PDF: 3 pages
Proc. SPIE 2673, Ophthalmic Technologies VI, (17 May 1996); doi: 10.1117/12.240056
Show Author Affiliations
Bernard Duchesne, Univ. of Miami School of Medicine (United States), and Univ. Liege (Belgium)
Jean-Marie A. Parel, Univ. of Miami School of Medicine (United States)
Hopital de l'Hotel-Dieu/Univ. de Paris (France)
INSERM (France)
Sabine Gautier, Univ. of Miami School of Medicine (United States)
Fabrice Manns, Univ. of Miami School of Medicine (United States)
Hiroyuki Kondo, Univ. of Miami School of Medicine (United States) and Fukuoka Univ. (Japan)
Emmanuel Lacombe, Univ. of Miami School of Medicine (United States)
Jean-Marc Legeais, Hopital de l'Hotel-Dieu/Univ. de Paris (France) and INSERM (France)
E. Alfonso, Univ. of Miami School of Medicine (United States)


Published in SPIE Proceedings Vol. 2673:
Ophthalmic Technologies VI
Jean-Marie A. Parel; Karen Margaret Joos; Pascal O. Rol, Editor(s)

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