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Proceedings Paper

Update on fluorescence spectroscopy studies of diseased skin
Author(s): Haishan Zeng; Harvey Lui; David I. McLean; Calum E. MacAulay; Branko Palcic
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Paper Abstract

This is a progress report on our ongoing fluorescence spectroscopy studies of diseased skin. A PC plug-in spectrometer has been used clinically to collect autofluorescence and diffuse reflectance spectral data from various skin lesions including skin cancer. To date, over 100 patients with a total of over 180 diseased skin sites have been measured and our database on the spectroscopic properties of diseased skin has been enlarged accordingly. Analysis of these preliminary data confirmed our preliminary observations that certain types of skin lesions possess consistent characteristic autofluorescence and diffuse reflectance properties. A new method of data analysis, spectra ratioing, provides new features to aid the optical diagnosis of skin lesions.

Paper Details

Date Published: 17 May 1996
PDF: 3 pages
Proc. SPIE 2671, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI, (17 May 1996); doi: 10.1117/12.240008
Show Author Affiliations
Haishan Zeng, British Columbia Cancer Research Ctr. (Canada)
Harvey Lui, British Columbia Cancer Research Ctr. (Canada)
Vancouver Hospital and Health Sciences Ctr./Univ. of British Columbia (Canada)
David I. McLean, British Columbia Cancer Research Ctr. (Canada)
Vancouver Hospital and Health Sciences Ctr./Univ. of British Columbia (Canada)
Calum E. MacAulay, British Columbia Cancer Research Ctr. (Canada)
Branko Palcic, British Columbia Cancer Research Ctr. (Canada)


Published in SPIE Proceedings Vol. 2671:
Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI
C. Thomas Vangsness; Kenneth Eugene Bartels; Lawrence S. Bass; Graham M. Watson; R. Rox Anderson; R. Rox Anderson; Royice B. Everett; Douglas E. Ott; Reza S. Malek; Rodney A. White; Lloyd P. Tate; Aaron P. Perlmutter, Editor(s)

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