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Proceedings Paper

Simulation and analysis of dynamic brain PET images
Author(s): Jeffrey T. Yap; Chin-Tu Chen; Malcolm Cooper
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Paper Abstract

We have developed a software package which combines the simulation and analysis of dynamic brain images acquired by positron emission tomography. In the spatial domain, standard digitized phantoms are used to create spatial maps which represent various structures in the brain. In the temporal domain, kinetic models are used to simulate the dynamics at the pixel level for each time-activity curve. Physical characteristics such as spatial resolution and noise are then modeled on individual image frames. This software has been used in the case of [18F]fluorodeoxyglucose studies to produce realistic simulations which were further analyzed to confirm previous findings based on real clinical data.

Paper Details

Date Published: 8 April 1996
PDF: 5 pages
Proc. SPIE 2709, Medical Imaging 1996: Physiology and Function from Multidimensional Images, (8 April 1996); doi: 10.1117/12.237869
Show Author Affiliations
Jeffrey T. Yap, Univ. of Chicago (United States)
Chin-Tu Chen, Univ. of Chicago (United States)
Malcolm Cooper, Univ. of Chicago (United States)


Published in SPIE Proceedings Vol. 2709:
Medical Imaging 1996: Physiology and Function from Multidimensional Images
Eric A. Hoffman, Editor(s)

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