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Proceedings Paper

Optical spectroscopy of benign and malignant breast tissues
Author(s): Yuanlong Yang; Alvin Katz; Edward J. Celmer; Margaret Zurawska-Szczepaniak; Robert R. Alfano
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Paper Abstract

Fluorescence spectroscopy was applied to characterize normal, malignant and adipose breast tissues. Excitation, emission, and synchronized diffusive reflectance spectral scans were measured on over one hundred specimens for the purpose of developing an improved spectroscopic diagnostic technique. These techniques were able to successfully distinguish malignant tissue from adipose glandular fibrous and normal tissue. A sensitivity of 91% for fifty-six (56) malignant specimens with specificity of 91% for forty-six (46) benign tissue specimens has been achieved, using pathology as the golden standard.

Paper Details

Date Published: 5 April 1996
PDF: 4 pages
Proc. SPIE 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy, (5 April 1996); doi: 10.1117/12.237597
Show Author Affiliations
Yuanlong Yang, CUNY/City College (United States)
Alvin Katz, CUNY/City College (United States)
Edward J. Celmer, St. Vincent's Medical Ctr. of Richmond (United States)
Margaret Zurawska-Szczepaniak, St. Vincent's Medical Ctr. of Richmond (United States)
Robert R. Alfano, CUNY/City College (United States)


Published in SPIE Proceedings Vol. 2679:
Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy
Robert R. Alfano; Abraham Katzir, Editor(s)

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