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Proceedings Paper

Vertical cavity surface-emitting laser scanning cytometer for high-speed analysis of cells
Author(s): Paul Lee Gourley; Anthony E. McDonald; Mark F. Gourley
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Paper Abstract

We have constructed a new semiconductor laser device that may be useful in high speed characterization of cell morphology for diagnosis of disease. This laser device has critical advantages over conventional cell florescence detection methods since it provides intense, monochromatic, low-divergence light signals that are emitted from lasing modes confined by a cell. Further, the device integrates biological structures with semiconductor materials at the wafer level to reduce device size and simplify cell preparation. In this paper we discuss operational characteristics of the prototype cytometer and present preliminary data for blood cells and dielectric spheres.

Paper Details

Date Published: 5 April 1996
PDF: 11 pages
Proc. SPIE 2679, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy, (5 April 1996); doi: 10.1117/12.237581
Show Author Affiliations
Paul Lee Gourley, Sandia National Labs. (United States)
Anthony E. McDonald, Sandia National Labs. (United States)
Mark F. Gourley, National Institutes of Health (United States)


Published in SPIE Proceedings Vol. 2679:
Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy
Robert R. Alfano; Abraham Katzir, Editor(s)

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