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Proceedings Paper

SQUID neuromagnetometric reconstruction of brain activity
Author(s): Manbir Singh; R. Ricardo Brechner; Koichi Oshio; Richard M. Leahy; Victor W. Henderson
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Paper Abstract

Ionic flow associated with neural activation of the brain produces a magnetic field that can be measured outside the head in a magnetically unshielded room using a highly sensitive neuromagnetometer based on a superconducting quantum interference device (SQUID). Reconstruction of images portraying the tomographic distribution of neural generators (assumed to be current dipoles) of the neuromagnetic field, a modality that we have termed "neuromagnetic imaging" or NMI, represents a powerful noninvasive method of dynamic functional imaging dependent upon brain structure and activity. Reconstruction in NMI, i.e., the inverse problem, however, has no unique solution and requires incorporation of modeling constraints for practical implementation. Results of several phantom and test-object studies and a preliminary human study to develop the method of NM! under various modeling constraints are presented.

Paper Details

Date Published: 1 November 1990
PDF: 10 pages
Proc. SPIE 1351, Digital Image Synthesis and Inverse Optics, (1 November 1990); doi: 10.1117/12.23654
Show Author Affiliations
Manbir Singh, Univ. of Southern California (United States)
R. Ricardo Brechner, Univ. of Southern California (United States)
Koichi Oshio, Univ. of Southern California (United States)
Richard M. Leahy, Univ. of Southern California (United States)
Victor W. Henderson, Univ. of Southern California (United States)


Published in SPIE Proceedings Vol. 1351:
Digital Image Synthesis and Inverse Optics
Arthur F. Gmitro; Paul S. Idell; Ivan J. LaHaie, Editor(s)

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