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Optoelectronic method for the determination of synthetic cannabinoids and their metabolites
Author(s): Monica Ionica Streche; Georgeta Marcela Bican; Jeni Carla Colev; Mihai Radu; Raluca-Andreea Băjănaru; Paul Şchiopu; Marian Vlădescu; Radu Macovei; Mihai Ionică
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Paper Abstract

Establishing an optoelectronic method for the determination of synthetic cannabinoids and their metabolites is necessary because synthetic cannabinoids are a group of psychoactive compounds designed to mimic the effects of marijuana. These compounds are usually sprayed on natural plants in order to be smoked. Several synthetic cannabinoids can be found on these smoked plants simultaneously. Their effective dose is lower than that of natural marijuana but with high psychoactive potency [1]. Due to their high potential for abuse and availability, these compounds are considered to be narcotic drugs. Thus, there has been an increased demand for the development of sensitive, reliable, robust and sustainable analytical methods for the identification and quantification of these compounds by clinical, forensic and toxicological laboratories [2].

The method presented in the paper will be based on liquid chromatography with a mass spectrometer detector (LCMS/ MS). The paper aims to obtain, using the developed method, the mass spectra of synthetic cannabinoids and their metabolites. The mass spectrum represents the relative abundance of ions resulting from an ionization process of a family of molecules. This is a unique feature for each compound, which allows identification of a substance from a matrix of unknown substances [3].

Paper Details

Date Published: 31 December 2018
PDF: 5 pages
Proc. SPIE 10977, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX, 109773K (31 December 2018); doi: 10.1117/12.2324798
Show Author Affiliations
Monica Ionica Streche, Univ. Politehnica of Bucharest (Romania)
Georgeta Marcela Bican, Doping Control Lab. (Romania)
Jeni Carla Colev, Doping Control Lab. (Romania)
Mihai Radu, Doping Control Lab. (Romania)
Raluca-Andreea Băjănaru, Univ. Politehnica of Bucharest (Romania)
Paul Şchiopu, Univ. Politehnica of Bucharest (Romania)
Marian Vlădescu, Univ. Politehnica of Bucharest (Romania)
Radu Macovei, Univ. of Medicine and Pharmacy "Carol Davila" (Romania)
Mihai Ionică, Doping Control Lab. (Romania)
Military-Medical Scientific Research Ctr. (Romania)


Published in SPIE Proceedings Vol. 10977:
Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX
Marian Vladescu; Razvan D. Tamas; Ionica Cristea, Editor(s)

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