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High temporal and spatial pattern stimulation to manipulate brain function
Author(s): Hiroaki Wake; Koichiro Haruwaka; Kogyoku Zen; Osamu Matoba
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Paper Abstract

In the central nervous system (CNS), glial cells, originally termed “nervenkitt,” recently focused because of the understanding of their physiological functions. Here, we focused how glial cell regulates the function of neuronal circuits using in vivo two photon microscope. In this research, we visualized neural activity in the motor cortex during motor learning using in vivo two photon microscope to understand the abnormality of neural activity associated with impaired behavior output with myelin dysregulation. We further demonstrate the optogenetic stimulation to compensate the abnormal activity of neural activity to rescue the learning disability.

Paper Details

Date Published: 24 April 2018
PDF: 3 pages
Proc. SPIE 10711, Biomedical Imaging and Sensing Conference, 1071102 (24 April 2018); doi: 10.1117/12.2323184
Show Author Affiliations
Hiroaki Wake, Kobe Univ. of Graduate School of Medicine (Japan)
Koichiro Haruwaka, Kobe Univ. of Graduate School of Medicine (Japan)
Kogyoku Zen, Kobe Univ. (Japan)
Osamu Matoba, Kobe Univ. (Japan)


Published in SPIE Proceedings Vol. 10711:
Biomedical Imaging and Sensing Conference
Toyohiko Yatagai; Yoshihisa Aizu; Osamu Matoba; Yasuhiro Awatsuji; Yuan Luo, Editor(s)

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