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Proceedings Paper

Self-assembled and supported BLMs as an adaptive material for biotechnology
Author(s): Angelica L. Ottova-Leitmannova; Vladimir Tvarozek; T. Hianik; Tiean Zhou; W. Ziegler; H. Ti Tien
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Paper Abstract

Cell membranes play a vital role in energy conversion, information processing and signal transduction. This is owing to the fact that most physiological activities involve lipid bilayer- based receptor-ligand interactions. Some of the outstanding examples are ATP synthesis, ion transport, antigen-antibody binding, and gated channels. One approach to study these interactions in vitro is facilitated by employing artificial BLMs (bilayer lipid membranes). Our current efforts have been focused on ion and/or molecular selectivity and specificity using recently available self-assembled BLMs on solid support (i.e. s-BLMs) which, with their enhanced stability, greatly aid in research areas of membrane biochemistry, biophysics, and cell biology as well as in biosensor designs and molecular devices development. In this report, our recent work along with the experiments done in collaboration with others on s-BLMs are presented.

Paper Details

Date Published: 9 February 1996
PDF: 8 pages
Proc. SPIE 2716, Smart Structures and Materials 1996: Smart Materials Technologies and Biomimetics, (9 February 1996); doi: 10.1117/12.232135
Show Author Affiliations
Angelica L. Ottova-Leitmannova, Michigan State Univ. (USA) and Slovak Technical Univ. (Slovak Republic)
Vladimir Tvarozek, Slovak Technical Univ. (Slovak Republic)
T. Hianik, Slovak Technical Univ. and Comenius Univ. (Slovak Republic)
Tiean Zhou, Michigan State Univ. (United States)
W. Ziegler, Slovak Technical Univ. and Comenius Univ. (Slovak Republic)
H. Ti Tien, Michigan State Univ. (USA) and Slovak Technical Univ. (Slovak Republic)


Published in SPIE Proceedings Vol. 2716:
Smart Structures and Materials 1996: Smart Materials Technologies and Biomimetics
Andrew Crowson, Editor(s)

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