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Proceedings Paper

Trapping and manipulation of individual cells in the crowd
Author(s): Qian Zhao; Pan-pan Yu; Yin-mei Li; Lei Gong
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Paper Abstract

Manipulating single cell with optical tweezers in vitro or in vivo plays an important role in biological research, whereas the manipulation of individual cells might be affected by the neighbor cells especially in the crowd environment. To overcome this problem, an annular beam formed by the far-field Bessel beam is introduced to serve as an optical shield to protect the target cells from being disturbed. We demonstrate that an individual cell can be trapped and manipulated through the crowd cells. What’s more, the interaction between two cells can be investigated by using a dual-trap optical tweezers in the crowd environment with the help of the optical shield.

Paper Details

Date Published: 24 April 2018
PDF: 3 pages
Proc. SPIE 10712, Optical Manipulation Conference, 107121N (24 April 2018); doi: 10.1117/12.2318883
Show Author Affiliations
Qian Zhao, Univ. of Science and Technology of China (China)
Pan-pan Yu, Univ. of Science and Technology of China (China)
Yin-mei Li, Univ. of Science and Technology of China (China)
Hefei National Lab. for Physical Science at the Microscale (China)
Lei Gong, Univ. of Science and Technology of China (China)

Published in SPIE Proceedings Vol. 10712:
Optical Manipulation Conference
Takashige Omatsu; Hajime Ishihara; Keiji Sasaki, Editor(s)

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