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Proceedings Paper

Application of laser scanning speckle-microscopy for high-resolution express diagnostics of chlamydial infection
Author(s): Sergey Ulyanov; Olga Larionova; Onega Ulianova; Sergey Zaitsev; Yury Saltykov; Tatiana Polyanina; Anna Lyapina; Nadezhda Filonova; Irina Subbotina; Irina Kalduzova; Sergey Utz; Yulia Moiseeva; Valentina Feodorova
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Paper Abstract

Method of speckle-microscopy has been adapted to the problem of detection of Chlamydia trachomatis microbial cells in clinical samples. Prototype of laser scanning speckle-microscope has been designed. Spatial resolution and output characteristics of this microscope have been analyzed for the case of scanning of C. trachomatis bacteria inclusions – Elementary Bodies (EBs) inside the human cells, fixed on the glass. It has been demonstrated, that presence of C. trachomatis microbial cells in the sample can be easily detected using speckle microscopy.

Paper Details

Date Published: 26 April 2018
PDF: 9 pages
Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107160N (26 April 2018); doi: 10.1117/12.2314703
Show Author Affiliations
Sergey Ulyanov, Saratov State Univ. (Russian Federation)
Federal Research Ctr. for Virology and Microbiology, Pokrov (Russian Federation)
Federal Research Ctr. for Virology and Microbiology, Saratov (Russian Federation)
Olga Larionova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Onega Ulianova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Sergey Zaitsev, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Yury Saltykov, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Tatiana Polyanina, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Anna Lyapina, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Nadezhda Filonova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Irina Subbotina, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Irina Kalduzova, Saratov State Univ. (Russian Federation)
Saratov State Medical Univ. (Russian Federation)
Sergey Utz, Saratov State Medical Univ. (Russian Federation)
Yulia Moiseeva, Saratov State Medical Univ. (Russian Federation)
Valentina Feodorova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10716:
Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX
Valery V. Tuchin; Elina A. Genina; Vladimir L. Derbov; Dmitry Engelevich Postnov, Editor(s)

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