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Detection of the presence of Chlamydia trachomatis bacteria using diffusing wave spectroscopy with a small number of scatterers
Author(s): Sergey Ulyanov; Onega Ulianova; Nadezhda Filonova; Yulia Moiseeva; Sergey Zaitsev; Yury Saltykov; Tatiana Polyanina; Anna Lyapina; Irina Kalduzova; Olga Larionova; Sergey Utz; Valentina Feodorova
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Paper Abstract

Theory of diffusing wave spectroscopy has been firstly adapted to the problem of rapid detection of Chlamydia trachomatis bacteria in blood samples of Chlamydia patients. Formula for correlation function of temporal fluctuations of speckle intensity is derived for the case of small number of scattering events. Dependence of bandwidth of spectrum on average number of scatterers is analyzed. Set-up for detection of the presence of C. trachomatis cells in aqueous suspension is designed. Good agreement between theoretical results and experimental data is shown. Possibility of detection of the presence of C. trachomatis cells in probing volume using diffusing wave spectroscopy with a small number of scatterers is successfully demonstrated for the first time.

Paper Details

Date Published: 26 April 2018
PDF: 10 pages
Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107160O (26 April 2018); doi: 10.1117/12.2314570
Show Author Affiliations
Sergey Ulyanov, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Univ. (Russian Federation)
Onega Ulianova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Nadezhda Filonova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Yulia Moiseeva, Saratov State Medical Univ. (Russian Federation)
Sergey Zaitsev, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Yury Saltykov, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Tatiana Polyanina, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Anna Lyapina, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Irina Kalduzova, Saratov State Univ. (Russian Federation)
Saratov State Medical Univ. (Russian Federation)
Olga Larionova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)
Sergey Utz, Saratov State Medical Univ. (Russian Federation)
Valentina Feodorova, Federal Research Ctr. for Virology and Microbiology (Russian Federation)
Saratov State Agrarian Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10716:
Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX
Valery V. Tuchin; Elina A. Genina; Vladimir L. Derbov; Dmitry Engelevich Postnov, Editor(s)

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