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Proceedings Paper

Immune and antioxidizing response in cancer patients to photodynamic therapy with photohem and photosens as photosensitizers
Author(s): Raisa I. Yakubovskaya; Victor V. Sokolov; H. R. Nemtzova; Victor K. Oganezov; I. Y. Scherbitskaya; H. V. Filonenko; E. I. Aristarkhova; Valery I. Chissov
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Paper Abstract

Free radicals are the main basis of anticancer effect of photodynamic therapy (PDT). At the same time, they cause different complications. The goal of this study is to investigate the changes in homeostasis of cancer patients under the influence of PDT. It was shown, as a result of study of antioxidizing and immune status of these patients, that there are significant deviations in their indices even before PDT. The treatment leads to further development of disbalance in these systems which demands correction. Several remedies have been offered for correction therapy. The application of these remedies causes the reduction of overstrain in antioxidizing defence and leads to decrease in cases of complications.

Paper Details

Date Published: 31 January 1996
PDF: 9 pages
Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); doi: 10.1117/12.230996
Show Author Affiliations
Raisa I. Yakubovskaya, P.A. Hertzen Moscow Research Oncology Institute (Russia)
Victor V. Sokolov, P.A. Hertzen Moscow Oncology Institute (Russia)
H. R. Nemtzova, P.A. Hertzen Oncological Institute (Russia)
Victor K. Oganezov, P.A. Hertzen Oncological Institute (Russia)
I. Y. Scherbitskaya, P.A. Hertzen Oncological Institute (Russia)
H. V. Filonenko, P.A. Hertzen Oncological Institute (Russia)
E. I. Aristarkhova, P.A. Hertzen Moscow Rearch Onology Institute (Russia)
Valery I. Chissov, P.A. Hertzen Moscow Research Oncology Institute (Russia)


Published in SPIE Proceedings Vol. 2625:
Photochemotherapy: Photodynamic Therapy and Other Modalities
Benjamin Ehrenberg; Giulio Jori; Johan Moan, Editor(s)

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