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Proceedings Paper

Photodynamic therapy of gastric cancer
Author(s): Sergey S. Kharnas; N. M. Kuzin; Victor Ya. Zavodnov; Olga A. Sclyanskaya; Kirill G. Linkov; Victor B. Loschenov; Gennadii A. Meerovich; Nadezgda L. Torshina; Alexander A. Stratonnikov; Rudolf W. Steiner
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Paper Abstract

Photodynamic therapy (PDT) with the use of laser endoscopic spectrum analyzer (LESA-5), the spectral-analyzing video-imaging system, Kr laser and various types of catheters for different tumor localizations, and Phthalocyanine aluminum photosensitizers in patients with gastric cancer was discussed. PDT was carried out in fifteen patients with gastric cancer. There were the following indications for PDT: early gastric cancer (3 patients), malignant stenosis of the cardia or pyloric portion of the stomach (4 patients), cancer of gastric stump with stenosis of gastrojejunal anastomosis (1 patient), preoperative treatment of patients with large but probably resectable gastric tumor size (7 patients). Usually we used 3 - 4 seances of laser treatment 10 - 30 minutes long. Concentration of photosensitizer in normal and malignant tissue was controlled by LESA-5. Treatment was monitored by spectral-analyzing video- imaging system in fluorescent light. The results show high efficiency of PDT especially in patients with early gastric cancer (necrosis of all tumor mass, i.e. complete regression of tumor). For all other patients we obtained partial regression of gastric cancer.

Paper Details

Date Published: 31 January 1996
PDF: 2 pages
Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); doi: 10.1117/12.230992
Show Author Affiliations
Sergey S. Kharnas, Moscow Medical Academy (Russia)
N. M. Kuzin, Moscow Medical Academy (Russia)
Victor Ya. Zavodnov, General Physics Institute (Russia)
Olga A. Sclyanskaya, Moscow Medical Academy (Russia)
Kirill G. Linkov, General Physics Institute (Russia)
Victor B. Loschenov, General Physics Institute (Russia)
Gennadii A. Meerovich, General Physics Institute (Russia)
Nadezgda L. Torshina, General Physics Institute (Russia)
Alexander A. Stratonnikov, General Physics Institute (Russia)
Rudolf W. Steiner, Institut fuer Lasertechnologien in der Medizin und Messtechnik an der Univ. Ulm (Germany)


Published in SPIE Proceedings Vol. 2625:
Photochemotherapy: Photodynamic Therapy and Other Modalities
Benjamin Ehrenberg; Giulio Jori; Johan Moan, Editor(s)

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