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Proceedings Paper

Peripheral substitution of pheophorbides and bacteriopheophorbides to promote inclusion into inert carrier systems for PDT
Author(s): Susanne Roehrs; Anja Ruebner-Heuermann; G. Hartwich; H. Scheer; Joerg G. Moser
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Paper Abstract

Pheophorbide a ethyl ester, pyropheophorbide a ethyl ester, and bacteriopheophorbide ethyl ester were substituted in 31-position with tert.butyl phenoxy or tert.butyl benzoic acid ester groups resp. in order to enhance affinity to (beta) -cyclodextrin dimers which form inclusion complexes with these photosensitizing drugs. This is a first step to construct inert transport complexes in order to photosensitize specifically cancer cells.

Paper Details

Date Published: 31 January 1996
PDF: 6 pages
Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); doi: 10.1117/12.230958
Show Author Affiliations
Susanne Roehrs, Heinrich-Heine-Univ. (Germany)
Anja Ruebner-Heuermann, Heinrich-Heine-Univ. (Germany)
G. Hartwich, Univ. Muenchen (Germany)
H. Scheer, Univ. Muenchen (Germany)
Joerg G. Moser, Heinrich-Heine-Univ. (Germany)

Published in SPIE Proceedings Vol. 2625:
Photochemotherapy: Photodynamic Therapy and Other Modalities
Benjamin Ehrenberg; Giulio Jori; Johan Moan, Editor(s)

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