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OCT-based characterization of the nonlinear properties of biological tissues in various states
Author(s): Alexandr A. Sovetsky; Ekaterina V. Gubarkova; Lev A. Matveev; Alexander L. Matveyev; Marina A. Sirotkina; Natalia D. Gladkova; Vladimir Y. Zaitsev
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Paper Abstract

Soft biological tissues manifest strongly pronounced nonlinear elastic behavior. Namely, the Young modulus for some tissues strongly depends on the applied stress. This property can be evaluated by compressional OCT elastography. We demonstrate the evaluation of nonlinear elastic properties on the samples of coronary arteries, breast cancer and cornea. The developed technique can be used for further investigation of the nonlinear properties of healthy and pathological tissues.

Paper Details

Date Published: 17 May 2018
PDF: 6 pages
Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 1068536 (17 May 2018); doi: 10.1117/12.2306246
Show Author Affiliations
Alexandr A. Sovetsky, Institute of Applied Physics (Russian Federation)
Ekaterina V. Gubarkova, Privolzhsky Research Medical Univ. (Russian Federation)
Lev A. Matveev, Institute of Applied Physics (Russian Federation)
Alexander L. Matveyev, Institute of Applied Physics (Russian Federation)
Privolzhsky Research Medical Univ. (Russian Federation)
Marina A. Sirotkina, Privolzhsky Research Medical Univ. (Russian Federation)
Natalia D. Gladkova, Privolzhsky Research Medical Univ. (Russian Federation)
Vladimir Y. Zaitsev, Institute of Applied Physics (Russian Federation)
Privolzhsky Research Medical Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10685:
Biophotonics: Photonic Solutions for Better Health Care VI
Jürgen Popp; Valery V. Tuchin; Francesco Saverio Pavone, Editor(s)

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