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Application of infrared imaging for monitoring retinal vascular network: an electric circuit analogy approach
Author(s): Xunfei Zhou; Sheng-Jen Hsieh
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Paper Abstract

It is well established that diabetes is linked with changes in ocular hemodynamics and retinal microaneurysms. However, it is difficult to diagnose a microaneurysm in a retinal vascular network using a traditional eye exam. The hypothesis of this study is that an overflow in the retinal vascular network will result in a temperature increase, and a microaneurysm could create a local hot spot. Therefore, this work investigates the possibility of applying infrared thermography to detect abnormal blood flow. As a precursor to human or animal testing, an electrical resistance network was used to simulate blood flow (using an electrical circuit analogy). An electrical signal with varied frequencies and peak voltages was used as the heating source. An infrared camera was used to acquire thermography images from the electrical resistance network. Thermal characteristics of the network were able to be derived from the images, suggesting that a timedependent and spatially resolved temperature mapping can be obtained and quantitatively analyzed. Moreover, combined with numerical simulation, the effect of blood flow change on surface temperature variation was investigated. This approach provides a way to apply thermal infrared imaging in diagnosis of retinal vascular diseases.

Paper Details

Date Published: 14 May 2018
PDF: 9 pages
Proc. SPIE 10661, Thermosense: Thermal Infrared Applications XL, 1066113 (14 May 2018); doi: 10.1117/12.2305570
Show Author Affiliations
Xunfei Zhou, Texas A&M Univ. (United States)
Sheng-Jen Hsieh, Texas A&M Univ. (United States)


Published in SPIE Proceedings Vol. 10661:
Thermosense: Thermal Infrared Applications XL
Douglas Burleigh; Jaap de Vries, Editor(s)

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