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Probing tissue multifractality for optical diagnosis of diabetic retinopathy
Author(s): Sawon Pratiher; Sabyasachi Mukhopadhyay; Sukanya Mukherjee; Ritwik Barman; Gautham Pasupuleti; Jay Chhablani; Prasanta K. Panigrahi
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Paper Abstract

Diabetic Retinopathy (DR) is one of the most dominant diseases across the globe which causes blindness. In this manuscript, we have probed tissue multifractality in order to identify the submicron level changes in medium refractive indices due to progress of diabetic retinopathy from mild to severe stages. Hence the quantification of multifractal parameters like Hurst exponent (measurement of correlation) and width of singularity (measurement of heterogeneity) have been executed. As we proceed from healthy to different stages (mild, moderate and severe) of diabetic retinopathy, there are decrement of Hurst exponent value, whereas, width of singularity spectrum increases. In general, the use of multifractal analysis on in vivo diabetic retinopathy images lead to a diagnostic modality as a potential statistical biomarker.

Paper Details

Date Published: 24 May 2018
PDF: 4 pages
Proc. SPIE 10679, Optics, Photonics, and Digital Technologies for Imaging Applications V, 1067906 (24 May 2018); doi: 10.1117/12.2305454
Show Author Affiliations
Sawon Pratiher, Indian Institute of Technology Kanpur (India)
Sabyasachi Mukhopadhyay, Indian Institute of Science Education and Research Kolkata (India)
Sukanya Mukherjee, Univ. of Engineering & Management (India)
Ritwik Barman, Indian Institute of Science Education and Research Kolkata (India)
Gautham Pasupuleti, Biodesign Innovation Labs (India)
Jay Chhablani, LV Prasad Eye Institute (India)
Prasanta K. Panigrahi, Indian Institute of Science Education and Research Kolkata (India)


Published in SPIE Proceedings Vol. 10679:
Optics, Photonics, and Digital Technologies for Imaging Applications V
Peter Schelkens; Touradj Ebrahimi; Gabriel Cristóbal, Editor(s)

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