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Proceedings Paper

Efficacy and safety of endoscopic Nd:YAG laser photocoagulation of flat colorectal adenomas
Author(s): Pasquale Spinelli; Andrea Mancini; Marco Dal Fante; Rocco Cunsolo
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Paper Abstract

The purpose of this study was to evaluate the efficacy and safety of endoscopic Nd:YAG laser photocoagulation for the treatment of flat colorectal adenomas. From January 1982 to December 1994, 222 lesions were treated in 216 patients. Initial eradication was obtained in 96% of lesions with a diameter less than 1 cm, in 89% of lesions with a diameter between 1 and 4 cm, and in 64% of lesions with a diameter greater than 4 cm. According to the histology, a complete disappearance was obtained in 94% of tubular, in 89% of tubulovillous, and in 80% of villous adenomas. Adenomas with severe dysplasia or foci of invasive carcinoma were eradicated in 76% and in 75% of cases, respectively. During a median follow- up of 24 months (3 - 129 months), recurrences developed in 46 of the 186 initially cured lesions (25%). All recurrent lesions were submitted to Nd:YAG laser photocoagulation, obtaining eradication in 37/46 (80%) of the cases. Malignant degeneration occurred in 6% of lesions. Complications related to laser treatments were observed in 5% of patients.

Paper Details

Date Published: 19 January 1996
PDF: 5 pages
Proc. SPIE 2623, Medical Applications of Lasers III, (19 January 1996); doi: 10.1117/12.230364
Show Author Affiliations
Pasquale Spinelli, Istituto Nazionale Tumori (Italy)
Andrea Mancini, Istituto Nazionale Tumori (Italy)
Marco Dal Fante, Istituto Nazionale Tumori (Italy)
Rocco Cunsolo, Istituto Nazionale Tumori (Italy)

Published in SPIE Proceedings Vol. 2623:
Medical Applications of Lasers III
Stephen G. Bown; Herbert J. Geschwind M.D.; Raimund Hibst; Frederic Laffitte; Giulio Maira; Roberto Pini; Hans-Dieter Reidenbach; Hans H. Scherer M.D.; Pasquale Spinelli, Editor(s)

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