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Proceedings Paper

Epidermal cooling during pulsed laser treatment of selected dermatoses
Author(s): J. Stuart Nelson; Bahman Anvari; B. Samuel Tanenbaum; Thomas E. Milner; Sol Kimel; Lars Othar Svaasand
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Paper Abstract

The clinical objective in laser treatment of selected dermatoses such as port wine stain (PWS), hemangioma and telangiectasia is to maximize thermal damage to the blood vessels, while at the same time minimizing nonspecific injury to the normal overlying epidermis. 'Dynamic' cooling of skin, whereby a cryogen is sprayed onto the surface for an appropriately short period of time (on the order of tens of milliseconds), may offer an effective method for eliminating epidermal thermal injury during laser treatment. We present theoretical and experimental investigations of the thermal response of skin to dynamic cooling in conjunction with pulsed laser irradiation at 585 nm. Computed temperature distributions indicate that cooling the skin immediately prior to pulsed laser irradiation with a cryogen spurt of tetrafluoroethane is an effective method for eliminating epidermal thermal injury during laser treatment of PWS. Experimental results show rapid reduction of skin surface temperature is obtained when using tetrafluoroethane spurts of 20 - 100 ms duration. Successful blanching of PWS without thermal injury to the overlying epidermis is accomplished.

Paper Details

Date Published: 19 January 1996
PDF: 8 pages
Proc. SPIE 2623, Medical Applications of Lasers III, (19 January 1996); doi: 10.1117/12.230299
Show Author Affiliations
J. Stuart Nelson, Univ. of California/Irvine (United States)
Bahman Anvari, Beckman Laser Institute and Medical Clinic and Harvey Mudd College (United States)
B. Samuel Tanenbaum, Harvey Mudd College (United States)
Thomas E. Milner, Beckman Laser Institute and Medical Clinic (United States)
Sol Kimel, Technion--Israel Institute of Technology (Israel)
Lars Othar Svaasand, Norwegian Institute of Technology (Norway)


Published in SPIE Proceedings Vol. 2623:
Medical Applications of Lasers III
Stephen G. Bown; Herbert J. Geschwind; Raimund Hibst; Frederic Laffitte; Giulio Maira; Roberto Pini; Hans-Dieter Reidenbach; Hans H. Scherer; Pasquale Spinelli, Editor(s)

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