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Proceedings Paper

Microscopic and macroscopic spectral peculiarities of cutaneous tumours
Author(s): Ekaterina Borisova; Tsanislava Genova; Petranka Troyanova; Ivan Terziev; Valery Zakharov; Ivan Bratchenko; Maria Lomova; Dmitry Gorin; Latchezar Avramov
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Paper Abstract

Autofluorescence spectral and confocal microscopic measurements were made on different cutaneous neoplastic lesions, namely basal cell carcinoma, squamous cell carcinoma, malignant melanoma, and their dysplastic forms – keratoacantoma, dysplastic nevi and benign lesions related – basal cell papiloma, seboreic keratosa and compound nevi using excitation at 405 nm. Spectroscopic investigations were made on in vivo and ex vivo tissue samples, and confocal microscopy investigations were made on ex vivo and eosin-haematoxilin stained thin slices of the tumours detected. Correlation between the spectral data received and the microscopic features observed was found, related to the morphological and biochemical alterations during neoplasia growth. Specific spectral features observed in each type of lesion investigated on micro and macro level would be presented and discussed.

Paper Details

Date Published: 7 December 2017
PDF: 6 pages
Proc. SPIE 10592, Biophotonics—Riga 2017, 1059202 (7 December 2017); doi: 10.1117/12.2296562
Show Author Affiliations
Ekaterina Borisova, Institute of Electronics (Bulgaria)
Saratov National Research State Univ. (Russian Federation)
Tsanislava Genova, Institute of Electronics (Bulgaria)
Petranka Troyanova, Univ. Hospital "Tsaritsa Yoanna-ISUL" (Bulgaria)
Ivan Terziev, Univ. Hospital "Tsaritsa Yoanna-ISUL" (Bulgaria)
Valery Zakharov, Samara National Research Univ. (Russian Federation)
Ivan Bratchenko, Samara National Research Univ. (Russian Federation)
Maria Lomova, Saratov National Research State Univ. (Russian Federation)
Dmitry Gorin, Saratov National Research State Univ. (Russian Federation)
Skolkovo Innovation Ctr. (Russian Federation)
Latchezar Avramov, Institute of Electronics (Bulgaria)


Published in SPIE Proceedings Vol. 10592:
Biophotonics—Riga 2017
Janis Spigulis, Editor(s)

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