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Proceedings Paper

Application of fluorescent and vibration spectroscopy for septic serum human albumin structure deformation during pathology
Author(s): A. Zyubin; E. Konstantinova; V. Slezhkin; K. Matveeva; I. Samusev; V. Bryukhanov
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Paper Abstract

In this paper we perform results of conformational analysis of septic human serum albumin (HSA) carried out by Raman spectroscopy (RS), infrared (IR) spectroscopy and fluorescent spectroscopy. The main vibrational groups were identified and analyzed for septic HSA and its health control. Comparison between Raman and IR results were done. Fluorescent spectral changes of Trp-214 group were analyzed. Application of Raman, IR spectroscopy, fluorescent spectroscopy for conformational changes study of HSA during pathology were shown.

Paper Details

Date Published: 7 December 2017
PDF: 6 pages
Proc. SPIE 10592, Biophotonics—Riga 2017, 1059205 (7 December 2017); doi: 10.1117/12.2295315
Show Author Affiliations
A. Zyubin, Immanuel Kant Baltic Federal Univ. (Russian Federation)
E. Konstantinova, Immanuel Kant Baltic Federal Univ. (Russian Federation)
V. Slezhkin, Immanuel Kant Baltic Federal Univ. (Russian Federation)
Kaliningrad State Technical Univ. (Russian Federation)
K. Matveeva, Immanuel Kant Baltic Federal Univ. (Russian Federation)
I. Samusev, Immanuel Kant Baltic Federal Univ. (Russian Federation)
V. Bryukhanov, Immanuel Kant Baltic Federal Univ. (Russian Federation)


Published in SPIE Proceedings Vol. 10592:
Biophotonics—Riga 2017
Janis Spigulis, Editor(s)

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