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Proceedings Paper

Automatical and accurate segmentation of cerebral tissues in fMRI dataset with combination of image processing and deep learning
Author(s): Zhenglun Kong; Junyi Luo; Shengpu Xu; Ting Li
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Paper Abstract

Image segmentation plays an important role in medical science. One application is multimodality imaging, especially the fusion of structural imaging with functional imaging, which includes CT, MRI and new types of imaging technology such as optical imaging to obtain functional images. The fusion process require precisely extracted structural information, in order to register the image to it. Here we used image enhancement, morphometry methods to extract the accurate contours of different tissues such as skull, cerebrospinal fluid (CSF), grey matter (GM) and white matter (WM) on 5 fMRI head image datasets. Then we utilized convolutional neural network to realize automatic segmentation of images in deep learning way. Such approach greatly reduced the processing time compared to manual and semi-automatic segmentation and is of great importance in improving speed and accuracy as more and more samples being learned. The contours of the borders of different tissues on all images were accurately extracted and 3D visualized. This can be used in low-level light therapy and optical simulation software such as MCVM. We obtained a precise three-dimensional distribution of brain, which offered doctors and researchers quantitative volume data and detailed morphological characterization for personal precise medicine of Cerebral atrophy/expansion. We hope this technique can bring convenience to visualization medical and personalized medicine.

Paper Details

Date Published: 13 February 2018
PDF: 7 pages
Proc. SPIE 10485, Optics and Biophotonics in Low-Resource Settings IV, 104850A (13 February 2018); doi: 10.1117/12.2293050
Show Author Affiliations
Zhenglun Kong, Institite of Biomedical Engineering (China)
Peking Union Medical College (China)
Junyi Luo, Institite of Biomedical Engineering (China)
Peking Union Medical College (China)
Northeastern Univ. (United States)
Shengpu Xu, Institite of Biomedical Engineering (China)
Peking Union Medical College (China)
Ting Li, Institite of Biomedical Engineering (China)
Peking Union Medical College (China)


Published in SPIE Proceedings Vol. 10485:
Optics and Biophotonics in Low-Resource Settings IV
David Levitz; Aydogan Ozcan; David Erickson, Editor(s)

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