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Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy
Author(s): Anna Ezerskaia; Silvania F. Pereira; H. Paul Urbach; Babu Varghese
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Paper Abstract

We show the feasibility of short wave infrared spectroscopy combined with tape stripping as a simple and noninvasive method for the analysis of lipids and the degree of hydration as a function of depth in the stratum corneum. The spectroscopic method utilizes differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lay “in between” the prominent water absorption bands. The results are compared with other biophysical devices such as Corneometer and Sebumeter.

Paper Details

Date Published: 14 February 2018
PDF: 6 pages
Proc. SPIE 10467, Photonics in Dermatology and Plastic Surgery 2018, 104670R (14 February 2018); doi: 10.1117/12.2291896
Show Author Affiliations
Anna Ezerskaia, Philips Research (Netherlands)
Delft Univ. of Technology (Netherlands)
Silvania F. Pereira, Delft Univ. of Technology (Netherlands)
H. Paul Urbach, Delft Univ. of Technology (Netherlands)
Babu Varghese, Philips Research (Netherlands)


Published in SPIE Proceedings Vol. 10467:
Photonics in Dermatology and Plastic Surgery 2018
Bernard Choi; Haishan Zeng, Editor(s)

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