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Novel liposomal technology applied in esophageal cancer treatment
Author(s): Chia-Hsien Yeh; Yei-San Hsieh; Pei-wen Yang; Leaf Huang; Yih-Chih Hsu
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Paper Abstract

Cisplatin (CDDP) has been commonly used as a chemotherapeutic drug, mainly used for the treatment of malignant epithelial cell tumors. We have developed a new method based on innovative lipid calcium phosphate, which encapsulated hydrophobic drugs to form liposomal nanoparticles. Esophageal cancer xenograft model was used to investigate the efficacy of liposomal nanoparticles. and it showed good therapeutic efficacy with lower side effects. Liposomal nanoparticles exhibited a better therapeutic effect than that of conventional CDDP.

Paper Details

Date Published: 19 February 2018
PDF: 5 pages
Proc. SPIE 10495, Biophotonics and Immune Responses XIII, 104950D (19 February 2018); doi: 10.1117/12.2291494
Show Author Affiliations
Chia-Hsien Yeh, Chung Yuan Christian Univ. (Taiwan)
Yei-San Hsieh, Taoyuan General Hospital (Taiwan)
Pei-wen Yang, National Taiwan Univ. Hospital (Taiwan)
Leaf Huang, Chung Yuan Christian Univ. (Taiwan)
Univ. of North Carolina at Chapel Hill (United States)
Yih-Chih Hsu, Chung Yuan Christian Univ. (Taiwan)


Published in SPIE Proceedings Vol. 10495:
Biophotonics and Immune Responses XIII
Wei R. Chen, Editor(s)

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