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Cherenkov imaging for Total Skin Electron Therapy (TSET)
Author(s): Yunhe Xie; Heather Petroccia; Amit Maity; Tianshun Miao; Yihua Zhu; Petr Bruza; Brian W. Pogue; Jacqueline M. Andreozzi; John P. Plastaras; Lei Dong; Timothy C. Zhu
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Paper Abstract

Total Skin Electron Therapy (TSET) utilizes high-energy electrons to treat cancers on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high-energy electron beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to evaluate the dose uniformity on the surface of the patient in real-time. Each patient was also monitored during TSET via in-vivo detectors (IVD) in nine locations. Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed, and the viability of the system to provide clinical feedback was established.

Paper Details

Date Published: 5 March 2018
PDF: 10 pages
Proc. SPIE 10478, Molecular-Guided Surgery: Molecules, Devices, and Applications IV, 1047816 (5 March 2018); doi: 10.1117/12.2291441
Show Author Affiliations
Yunhe Xie, The Univ. of Pennsylvania Health System (United States)
Heather Petroccia, The Univ. of Pennsylvania Health System (United States)
Amit Maity, The Univ. of Pennsylvania Health System (United States)
Tianshun Miao, Thayer School of Engineering at Dartmouth (United States)
Yihua Zhu, The Univ. of Pennsylvania Health System (United States)
Petr Bruza, Thayer School of Engineering at Dartmouth (United States)
Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)
Jacqueline M. Andreozzi, Thayer School of Engineering at Dartmouth (United States)
John P. Plastaras, The Univ. of Pennsylvania Health System (United States)
Lei Dong, The Univ. of Pennsylvania Health System (United States)
Timothy C. Zhu, The Univ. of Pennsylvania Health System (United States)


Published in SPIE Proceedings Vol. 10478:
Molecular-Guided Surgery: Molecules, Devices, and Applications IV
Brian W. Pogue; Sylvain Gioux; Greg Biggs, Editor(s)

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