Share Email Print
cover

Proceedings Paper

Skull's acoustic attenuation and dispersion modeling on photoacoustic signal
Author(s): Leila Mohammadi; Hamid Behnam; Jahan Tavakkoli; Mohammadreza Nasiriavanaki
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Despite the promising results of the recent novel transcranial photoacoustic (PA) brain imaging technology, it has been demonstrated that the presence of the skull severely affects the performance of this imaging modality. We theoretically investigate the effects of acoustic heterogeneity induced by skull on the PA signals generated from single particles, with firstly developing a mathematical model for this phenomenon and then explore experimental validation of the results. The model takes into account the frequency dependent attenuation and dispersion effects occur with wave reflection, refraction and mode conversion at the skull surfaces. Numerical simulations based on the developed model are performed for calculating the propagation of photoacoustic waves through the skull. The results show a strong agreement between simulation and ex-vivo study. The findings are as follow: The thickness of the skull is the most PA signal deteriorating factor that affects both its amplitude (attenuation) and phase (distortion). Also we demonstrated that, when the depth of target region is low and it is comparable to the skull thickness, however, the skull-induced distortion becomes increasingly severe and the reconstructed image would be strongly distorted without correcting these effects. It is anticipated that an accurate quantification and modeling of the skull transmission effects would ultimately allow for aberration correction in transcranial PA brain imaging.

Paper Details

Date Published: 28 February 2018
PDF: 6 pages
Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104946K (28 February 2018); doi: 10.1117/12.2291362
Show Author Affiliations
Leila Mohammadi, Islamic Azad Univ. (Iran, Islamic Republic of)
Hamid Behnam, Iran Univ. of Science and Technology (Iran, Islamic Republic of)
Jahan Tavakkoli, Ryerson Univ. (Canada)
Mohammadreza Nasiriavanaki, Wayne State Univ. (United States)


Published in SPIE Proceedings Vol. 10494:
Photons Plus Ultrasound: Imaging and Sensing 2018
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

© SPIE. Terms of Use
Back to Top