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Proceedings Paper

Novel approach to elucidate the nature of photomodulation therapy
Author(s): Vladislav V. Yakovlev; Michael L. Denton; Cherry C. Gonzalez; Gary D. Noojin
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Paper Abstract

Photobiomodulation therapy has been around for several decades with a number of applications increasing every year. However, the exact mechanisms of energy/signal transduction, which lead to the observed changes, and the lack of those in living cells, is still poorly understood. We propose and experimentally implement a novel research platform, which uses a microfluidic chip and controllable excitation condition to precisely initiate the process of photobiomodulation. Resonance Raman spectroscopy is employed to assess the structural transformational stages on different time-scales. We will present our first experimental results and discuss those results with respect to potential therapeutic applications.

Paper Details

Date Published: 27 February 2018
PDF: 5 pages
Proc. SPIE 10477, Mechanisms of Photobiomodulation Therapy XIII, 104770L (27 February 2018); doi: 10.1117/12.2291358
Show Author Affiliations
Vladislav V. Yakovlev, Texas A&M Univ. (United States)
Michael L. Denton, 711th Human Performance Wing, Airman Systems Directorate (United States)
Cherry C. Gonzalez, 711th Human Performance Wing, Airman Systems Directorate (United States)
Gary D. Noojin, Engility Corp. (United States)


Published in SPIE Proceedings Vol. 10477:
Mechanisms of Photobiomodulation Therapy XIII
Michael R. Hamblin; James D. Carroll; Praveen Arany, Editor(s)

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