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Proceedings Paper

Transurethral illumination probe design for deep photoacoustic imaging of prostate
Author(s): Min Ai; Tim Salcudean; Robert Rohling; Purang Abolmaesumi; Shuo Tang
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Paper Abstract

Photoacoustic (PA) imaging with internal light illumination through optical fiber could enable imaging of internal organs at deep penetration. We have developed a transurethral probe with a multimode fiber inserted in a rigid cystoscope sheath for illuminating the prostate. At the distal end, the fiber tip is processed to diffuse light circumferentially over 2 cm length. A parabolic cylinder mirror then reflects the light to form a rectangular-shaped parallel beam which has at least 1 cm2 at the probe surface. The relatively large rectangular beam size can reduce the laser fluence rate on the urethral wall and thus reduce the potential of tissue damage. A 3 cm optical penetration in chicken tissue is achieved at a fluence rate around 7 mJ/cm2 . For further validation, a prostate phantom was built with similar optical properties of the human prostate. A 1.5 cm penetration depth is achieved in the prostate mimicking phantom at 10 mJ/cm2 fluence rate. PA imaging of prostate can potentially be carried out in the future by combining a transrectal ultrasound transducer and the transurethral illumination.

Paper Details

Date Published: 19 February 2018
PDF: 7 pages
Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104940C (19 February 2018); doi: 10.1117/12.2291164
Show Author Affiliations
Min Ai, The Univ. of British Columbia (Canada)
Tim Salcudean, The Univ. of British Columbia (Canada)
Robert Rohling, The Univ. of British Columbia (Canada)
Purang Abolmaesumi, The Univ. of British Columbia (Canada)
Shuo Tang, The Univ. of British Columbia (Canada)

Published in SPIE Proceedings Vol. 10494:
Photons Plus Ultrasound: Imaging and Sensing 2018
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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