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Clinical photoacoustic computed tomography of the human breast in vivo within a single breath hold
Author(s): Li Lin; Peng Hu; Junhui Shi; Catherine M. Appleton; Konstantin Maslov; Lihong V. Wang
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Paper Abstract

We have developed a single-breath-hold photoacoustic computed tomography (SBH-PACT) system to detect tumors and reveal detailed angiographic information about human breasts. SBH-PACT provides high spatial and temporal resolutions with a deep in vivo penetration depth of over 4 cm. A volumetric breast image can be acquired by scanning the breast within a single breath hold (~15 sec). We imaged a healthy female volunteer and seven breast cancer patients. SBH-PACT clearly identified all tumors by revealing higher blood vessel densities and lower compliance associated with the tumors

Paper Details

Date Published: 22 March 2018
PDF: 7 pages
Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104942X (22 March 2018); doi: 10.1117/12.2290987
Show Author Affiliations
Li Lin, California Institute of Technology (United States)
Peng Hu, Washington Univ. in St. Louis (United States)
Junhui Shi, Washington Univ. in St. Louis (United States)
Catherine M. Appleton, Washington Univ. School of Medicine in St. Louis (United States)
Konstantin Maslov, California Institute of Technology (United States)
Lihong V. Wang, California Institute of Technology (United States)


Published in SPIE Proceedings Vol. 10494:
Photons Plus Ultrasound: Imaging and Sensing 2018
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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