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Proceedings Paper

In vivo and ex vivo characterization of a novel Er fiber laser system for fractional treatment of soft oral tissues
Author(s): Ksenia Shatilova; Georgii Aloian; Maria Karabut; Valentina Ryabova; Ilya V. Yaroslavsky; Gregory Altshuler
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Paper Abstract

In this work, we present the first histological in vivo and ex vivo study of effects of fractional Er fiber laser (wavelength 1550 nm, peak power 25 W) on keratinized gum and alveolar mucosa for gum regeneration. Biopsy with subsequent NBTC staining was used as primary evaluation technique. Ex vivo, porcine tissue model was used. Effects of pulse energy, beam diameter, and beam divergence were investigated in detail. It has been demonstrated that under optimal conditions columns up to 800 μm in depth could be reliably produced with 130 mJ pulses. Clinically, 2 subjects were treated and 4 punch biopsies were collected. The results were compared with ex vivo data. Both ex vivo and in vivo datasets suggest feasibility of a dental fractional system intended for gum regeneration.

Paper Details

Date Published: 8 February 2018
PDF: 7 pages
Proc. SPIE 10473, Lasers in Dentistry XXIV, 104730J (8 February 2018); doi: 10.1117/12.2290734
Show Author Affiliations
Ksenia Shatilova, NTO "IRE-Polus" (Russian Federation)
Georgii Aloian, Moscow Institute of Physics and Technology (Russian Federation)
Maria Karabut, Nizhny Novgorod State Medical Academy (Russian Federation)
Valentina Ryabova, Nizhny Novgorod State Medical Academy (Russian Federation)
Ilya V. Yaroslavsky, IPG Medical Corp. (United States)
Gregory Altshuler, IPG Medical Corp. (United States)

Published in SPIE Proceedings Vol. 10473:
Lasers in Dentistry XXIV
Peter Rechmann; Daniel Fried, Editor(s)

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